MODERATE — Monitor Closely
🟡 MODERATE — Resveratrol may increase Warfarin bleeding risk.
Evidence level: THEORETICAL
Resveratrol can mildly thin the blood on its own and may increase warfarin levels, raising bleeding risk.
Resveratrol has mild antiplatelet effects and may inhibit CYP enzymes involved in warfarin metabolism, potentially increasing INR.
If taking warfarin, consult your doctor before starting resveratrol. Monitor INR more frequently if you combine them.
High caution required. Fish oil, vitamin E, and nattokinase all have blood-thinning properties that can amplify Warfarin. CoQ10 and vitamin K can REDUCE warfarin effectiveness. Take at their normal times but inform your prescriber about ALL supplements. Request INR monitoring if starting or stopping any supplement while on an anticoagulant.
High-dose resveratrol, other blood thinners, elderly
Unusual bruising, prolonged bleeding, nosebleeds, blood in stool
Mention resveratrol to your anticoagulation clinic
Blood thinners have narrow safety margins. Instead of Resveratrol, consider safer options: CoQ10 (with INR monitoring), vitamin D3, or probiotics — these have minimal anticoagulant interactions. Always inform your anticoagulation clinic about any supplements.
Resveratrol can mildly thin the blood on its own and may increase warfarin levels, raising bleeding risk.
High caution required. Fish oil, vitamin E, and nattokinase all have blood-thinning properties that can amplify Warfarin. CoQ10 and vitamin K can REDUCE warfarin effectiveness. Take at their normal times but inform your prescriber about ALL supplements. Request INR monitoring if starting or stopping any supplement while on an anticoagulant.
Unusual bruising, prolonged bleeding, nosebleeds, blood in stool
Blood thinners have narrow safety margins. Instead of Resveratrol, consider safer options: CoQ10 (with INR monitoring), vitamin D3, or probiotics — these have minimal anticoagulant interactions. Always inform your anticoagulation clinic about any supplements.
Mention resveratrol to your anticoagulation clinic
Or browse the full interaction database (121,000+ pairs).