SAFE — No Known Interaction
🟢 SAFE — Metoprolol and Trimethoprim-Sulfamethoxazole can be taken together safely.
Evidence level: MODERATE
Metoprolol and Trimethoprim-Sulfamethoxazole are safe to take together based on current evidence. No adverse interactions reported.
No clinically significant interaction between Metoprolol and Trimethoprim-Sulfamethoxazole has been identified in medical literature.
No documented interaction between Metoprolol and Trimethoprim-Sulfamethoxazole. These are commonly prescribed together without issues. Your pharmacist reviews your full medication list for interactions with every new prescription.
Take each at their prescribed times. Most antibiotics don't significantly interact with beta-blockers, though macrolides (erythromycin, clarithromycin) can inhibit CYP3A4 metabolism of some beta-blockers like carvedilol, potentially increasing their effect. Monitor for dizziness or low heart rate.
Higher risk for: those with asthma or COPD, bradycardia, diabetes (may mask hypoglycemia symptoms), elderly, concurrent calcium channel blocker use, or peripheral vascular disease.
Monitor blood pressure and heart rate when combining Metoprolol with Trimethoprim-Sulfamethoxazole. Watch for: dizziness, lightheadedness (especially when standing up), fatigue, cold extremities, slow heartbeat, or swelling in ankles/feet. Check your blood pressure at home if possible. When to seek emergency help: Fainting, chest pain, heart rate below 50 bpm, severe dizziness, difficulty breathing, or allergic reactions (swelling of face, lips, or tongue).
No urgent need to discuss, but always keep your doctor informed of your full supplement and medication list. An up-to-date list helps them make the best treatment decisions.
These medications are safe to take together at standard doses. Continue taking as prescribed and keep your pharmacist informed of your complete medication list.
Metoprolol and Trimethoprim-Sulfamethoxazole are safe to take together based on current evidence. No adverse interactions reported.
Take each at their prescribed times. Most antibiotics don't significantly interact with beta-blockers, though macrolides (erythromycin, clarithromycin) can inhibit CYP3A4 metabolism of some beta-blockers like carvedilol, potentially increasing their effect. Monitor for dizziness or low heart rate.
Monitor blood pressure and heart rate when combining Metoprolol with Trimethoprim-Sulfamethoxazole. Watch for: dizziness, lightheadedness (especially when standing up), fatigue, cold extremities, slow heartbeat, or swelling in ankles/feet. Check your blood pressure at home if possible. When to seek emergency help: Fainting, chest pain, heart rate below 50 bpm, severe dizziness, difficulty breathing, or allergic reactions (swelling of face, lips, or tongue).
These medications are safe to take together at standard doses. Continue taking as prescribed and keep your pharmacist informed of your complete medication list.
No urgent need to discuss, but always keep your doctor informed of your full supplement and medication list. An up-to-date list helps them make the best treatment decisions.
Or browse the full interaction database (121,000+ pairs).