SAFE — No Known Interaction
🟢 SAFE — Lisinopril and Vitamin B3 can be taken together safely.
Evidence level: MODERATE
Lisinopril and Vitamin B3 are generally considered safe to use together. No adverse interactions have been reported in medical literature.
No clinically significant interaction between Lisinopril and Vitamin B3 has been identified in medical literature.
No interaction documented between Lisinopril and Vitamin B3. Always inform your healthcare provider about everything you take.
Take each at their normal times. Vitamin B3 with a meal. No major interactions between most vitamins and ACE inhibitors. Vitamin D supports kidney and cardiovascular health — both relevant when on ACE inhibitor therapy.
Higher risk for: those with renal impairment, hyperkalemia risk, concurrent potassium-sparing diuretics or potassium supplements, elderly, dehydrated patients, or those with bilateral renal artery stenosis.
Monitor blood pressure and heart rate when combining Lisinopril with Vitamin B3. Watch for: dizziness, lightheadedness (especially when standing up), fatigue, cold extremities, slow heartbeat, or swelling in ankles/feet. Check your blood pressure at home if possible. When to seek emergency help: Fainting, chest pain, heart rate below 50 bpm, severe dizziness, difficulty breathing, or allergic reactions (swelling of face, lips, or tongue).
No urgent discussion needed, but keep your provider informed. Say: "I take Lisinopril alongside Vitamin B3 — anything I should know?"
Safe combination at standard doses. Continue your medication as prescribed. Inform your doctor or pharmacist that you are using both, so they can monitor for any changes over time.
Lisinopril and Vitamin B3 are generally considered safe to use together. No adverse interactions have been reported in medical literature.
Take each at their normal times. Vitamin B3 with a meal. No major interactions between most vitamins and ACE inhibitors. Vitamin D supports kidney and cardiovascular health — both relevant when on ACE inhibitor therapy.
Monitor blood pressure and heart rate when combining Lisinopril with Vitamin B3. Watch for: dizziness, lightheadedness (especially when standing up), fatigue, cold extremities, slow heartbeat, or swelling in ankles/feet. Check your blood pressure at home if possible. When to seek emergency help: Fainting, chest pain, heart rate below 50 bpm, severe dizziness, difficulty breathing, or allergic reactions (swelling of face, lips, or tongue).
Safe combination at standard doses. Continue your medication as prescribed. Inform your doctor or pharmacist that you are using both, so they can monitor for any changes over time.
No urgent discussion needed, but keep your provider informed. Say: "I take Lisinopril alongside Vitamin B3 — anything I should know?"
Or browse the full interaction database (121,000+ pairs).