MAJOR — Use With Caution
🔴 CAUTION — Major interaction between Ginkgo Biloba and Aspirin. Avoid unless under direct medical supervision.
Evidence level: STRONG
Both Ginkgo and aspirin thin blood through different mechanisms. Together, significantly higher bleeding risk.
Ginkgo PAF inhibition + aspirin COX-1 inhibition = compounded antiplatelet/bleeding effects.
When combining Ginkgo Biloba with Aspirin, tell your doctor before any surgery or dental procedure. Watch for unusual bruising, bleeding gums, blood in stool, or prolonged bleeding from cuts.
Take Aspirin with food. Ginkgo Biloba can be taken at the same or different meal. Anti-inflammatory botanicals (turmeric, boswellia, willow bark) may have additive effects with NSAIDs — this could be beneficial but also increases GI irritation risk. Willow bark contains salicin (aspirin-like) and should not be doubled up with NSAIDs.
Higher risk with: older age (65+), history of GI bleeding, concurrent use of multiple blood-thinning agents, liver disease, heavy alcohol use, recent surgery.
Unusual bruising, bleeding gums, nosebleeds, blood in urine or stool, black tarry stools, prolonged bleeding from cuts, coughing up blood.
Ask your doctor: "Is there a safer alternative to Ginkgo Biloba that I can take with Aspirin?" Bring a list of ALL supplements and medications you take.
NSAID interactions often involve bleeding risk or kidney strain. Safer anti-inflammatory alternatives: curcumin/turmeric, omega-3 fish oil, or acetaminophen (for pain without anti-inflammatory effects). Use NSAIDs at the lowest effective dose for the shortest duration.
Both Ginkgo and aspirin thin blood through different mechanisms. Together, significantly higher bleeding risk.
Take Aspirin with food. Ginkgo Biloba can be taken at the same or different meal. Anti-inflammatory botanicals (turmeric, boswellia, willow bark) may have additive effects with NSAIDs — this could be beneficial but also increases GI irritation risk. Willow bark contains salicin (aspirin-like) and should not be doubled up with NSAIDs.
Unusual bruising, bleeding gums, nosebleeds, blood in urine or stool, black tarry stools, prolonged bleeding from cuts, coughing up blood.
NSAID interactions often involve bleeding risk or kidney strain. Safer anti-inflammatory alternatives: curcumin/turmeric, omega-3 fish oil, or acetaminophen (for pain without anti-inflammatory effects). Use NSAIDs at the lowest effective dose for the shortest duration.
Ask your doctor: "Is there a safer alternative to Ginkgo Biloba that I can take with Aspirin?" Bring a list of ALL supplements and medications you take.
Or browse the full interaction database (121,000+ pairs).