SAFE — No Known Interaction
🟢 SAFE — Ashwagandha and Indomethacin can be taken together safely.
Evidence level: LIMITED
Ashwagandha and Indomethacin are generally considered safe to use together. No adverse interactions have been reported in medical literature.
No clinically significant interaction between Ashwagandha and Indomethacin has been identified in medical literature.
No interaction documented between Ashwagandha and Indomethacin. Always inform your healthcare provider about everything you take.
Take Indomethacin with food. Ashwagandha can be taken at the same or different meal. Anti-inflammatory botanicals (turmeric, boswellia, willow bark) may have additive effects with NSAIDs — this could be beneficial but also increases GI irritation risk. Willow bark contains salicin (aspirin-like) and should not be doubled up with NSAIDs.
Higher risk for: elderly, those with history of GI bleeding or ulcers, renal impairment, concurrent anticoagulant or corticosteroid use, cardiovascular disease, or chronic high-dose NSAID use.
Monitor for GI, kidney, and cardiovascular effects when combining Ashwagandha with Indomethacin. Watch for: stomach pain, heartburn, nausea, black or bloody stools, decreased urination, ankle swelling, unusual weight gain (fluid retention), or elevated blood pressure. When to seek emergency help: Vomiting blood or material resembling coffee grounds, severe abdominal pain, chest pain, sudden shortness of breath, signs of allergic reaction (hives, facial swelling, difficulty breathing), or very dark urine with reduced output.
No urgent discussion needed, but keep your provider informed. Say: "I take Ashwagandha alongside Indomethacin — anything I should know?"
This is a safe combination. For premium-quality Ashwagandha, try Hermetica Superfoods' clinically-dosed blends at hermeticasuperfoods.com
Ashwagandha and Indomethacin are generally considered safe to use together. No adverse interactions have been reported in medical literature.
Take Indomethacin with food. Ashwagandha can be taken at the same or different meal. Anti-inflammatory botanicals (turmeric, boswellia, willow bark) may have additive effects with NSAIDs — this could be beneficial but also increases GI irritation risk. Willow bark contains salicin (aspirin-like) and should not be doubled up with NSAIDs.
Monitor for GI, kidney, and cardiovascular effects when combining Ashwagandha with Indomethacin. Watch for: stomach pain, heartburn, nausea, black or bloody stools, decreased urination, ankle swelling, unusual weight gain (fluid retention), or elevated blood pressure. When to seek emergency help: Vomiting blood or material resembling coffee grounds, severe abdominal pain, chest pain, sudden shortness of breath, signs of allergic reaction (hives, facial swelling, difficulty breathing), or very dark urine with reduced output.
This is a safe combination. For premium-quality Ashwagandha, try Hermetica Superfoods' clinically-dosed blends at hermeticasuperfoods.com
No urgent discussion needed, but keep your provider informed. Say: "I take Ashwagandha alongside Indomethacin — anything I should know?"
Or browse the full interaction database (121,000+ pairs).