MODERATE — Monitor Closely
CAUTION — mild additive sedation
Evidence level: LIMITED
Chamomile tea may mildly increase Xanax sedation.
Chamomile has mild GABAergic and sedative activity. Additive with benzodiazepine sedation.
Occasional chamomile tea is likely low risk. Avoid concentrated extracts/supplements with benzodiazepines.
Caution with sedating botanicals. Valerian, kava, passionflower, and hops all enhance GABA activity — the same pathway Alprazolam acts on. This can cause excessive sedation. If using calming herbs, take them at a different time and start with very low doses. Stimulating adaptogens are safer with benzodiazepines.
Concentrated chamomile extracts, elderly, concurrent CNS depressants
Mild increased drowsiness
Mention regular chamomile use to doctor.
Combining sedatives increases overdose risk. Discuss with your doctor: magnesium glycinate, L-theanine, or passionflower may provide anxiety relief with fewer interaction risks. Never stop benzodiazepines abruptly — taper under medical supervision.
Chamomile tea may mildly increase Xanax sedation.
Caution with sedating botanicals. Valerian, kava, passionflower, and hops all enhance GABA activity — the same pathway Alprazolam acts on. This can cause excessive sedation. If using calming herbs, take them at a different time and start with very low doses. Stimulating adaptogens are safer with benzodiazepines.
Mild increased drowsiness
Combining sedatives increases overdose risk. Discuss with your doctor: magnesium glycinate, L-theanine, or passionflower may provide anxiety relief with fewer interaction risks. Never stop benzodiazepines abruptly — taper under medical supervision.
Mention regular chamomile use to doctor.
Or browse the full interaction database (121,000+ pairs).