Zeaxanthin (3R,3'R)-β,β-carotene-3,3'-diol — Hermetica Encyclopedia
Named Bioactive Compounds · Carotenoid

Zeaxanthin (3R,3'R)-β,β-carotene-3,3'-diol

Preliminary Evidencecarotenoid

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The Short Answer

Zeaxanthin is a naturally occurring carotenoid found in colorful foods that accumulates in the eye, though clinical evidence for health benefits is not documented in this research.

PubMed Studies
0
Validated Benefits
Synergy Pairings
At a Glance
CategoryNamed Bioactive Compounds
GroupCarotenoid
Evidence LevelPreliminary
Synergy Pairings3

Health Benefits

Origin & History

Zeaxanthin is a xanthophyll carotenoid pigment with the chemical structure (3R,3'R)-β,β-carotene-3,3'-diol, synthesized in plants and some microorganisms. It occurs naturally in marigold flowers, corn, paprika, saffron, goji berries, egg yolk, and microalgae like Dunaliella salina (up to 11,270 μg/g). Commercial extraction from Tagetes erecta involves hexane extraction, saponification, and crystallization, while synthetic production uses the Wittig reaction, yielding 96-98% pure trans-(3R,3'R)-zeaxanthin.

The research dossier contains no information about traditional or historical uses of zeaxanthin in traditional medicine systems.Traditional Medicine

Scientific Research

The research dossier explicitly states that search results lack details on key human clinical trials, RCTs, or meta-analyses with PubMed PMIDs. No specific clinical evidence, study designs, sample sizes, or outcomes are provided in the sources.

Preparation & Dosage

No clinically studied dosage ranges for extracts, powders, or standardized forms are specified in the available research. Consult a healthcare provider before starting any new supplement.

Nutritional Profile

Synergy Stack

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Frequently Asked Questions

What is zeaxanthin?
Zeaxanthin is a xanthophyll carotenoid pigment found naturally in marigold flowers, corn, paprika, goji berries, and egg yolks. It has the chemical structure (3R,3'R)-β,β-carotene-3,3'-diol and accumulates in the eye's macula.
What are the benefits of zeaxanthin?
While zeaxanthin is known to accumulate in the eye's macula via a specific binding protein, the available research does not provide clinical evidence for specific health benefits in humans.
What is the recommended dosage?
No clinically studied dosage ranges are specified in the current research. Always consult a healthcare provider before starting any new supplement.
Are there any side effects?
The research provides no information on contraindications, drug interactions, pregnancy/nursing warnings, or maximum safe doses for zeaxanthin supplementation.
Can I take zeaxanthin with other supplements?
No drug or supplement interactions are documented in the available research. Consult your healthcare provider about potential interactions with your current medications or supplements.

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