
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Wild rose hips contain exceptionally high levels of vitamin C (up to 1,200 mg/100g) along with the galactolipid GOPO, which inhibits neutrophil chemotaxis and reduces inflammatory enzyme activity. These compounds scavenge free radicals (80-97% DPPH inhibition) and suppress COX-1/COX-2 enzymes by 65-73%, providing potent antioxidant and anti-inflammatory effects.

Reported Benefits (Provisional)
Origin & History

Wild Rose Hips (Rosa spp.) are the fruit of various wild rose species, native to temperate regions across the Northern Hemisphere. These small, red to orange fruits develop after the rose blooms, prized for their tangy flavor and exceptional nutritional value. They have long been valued for their health benefits and culinary versatility, particularly for immune and skin support.
Research Narrative (Provisional)
Scientific studies confirm Wild Rose Hips' significant antioxidant and immune-boosting properties, primarily attributed to their high vitamin C content. Research also supports their role in promoting skin health, digestive regularity, and reducing systemic inflammation.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Dietary fiber - Vitamins: C (outstanding source), A - Minerals: Potassium, Calcium, Magnesium - Phytochemicals: Polyphenols, Flavonoids
Reported Mechanism (Provisional)
Rose hips' bioactive compounds including phenolic acids (galloylquinic acid, ellagic acid), flavonoids (tiliroside, quercetin glycosides), and the galactolipid GOPO inhibit cyclooxygenase enzymes COX-1 (64.9%) and COX-2 (72.5%). These compounds scavenge reactive oxygen species, protect mitochondria from oxidative damage, and modulate inflammatory cytokine production. GOPO specifically inhibits neutrophil chemotaxis, reducing tissue infiltration and inflammatory cascade activation.
Clinical Narrative (Provisional)
Human clinical trial data for rose hips remains limited, with most evidence derived from preclinical studies. Animal studies demonstrate hepatoprotective effects at 500-750 mg/kg, reducing liver enzymes ALT/AST and lipid peroxidation markers while increasing albumin levels. In vitro studies show cytotoxic effects against HT29 colon cancer cells with IC50 of 7.89 μg/mL after 48 hours. While traditional use for arthritis is supported by GOPO's anti-inflammatory mechanisms, quantified human clinical outcomes with specific pain scores or efficacy rates are not available in current literature.
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