Tiger's Claw Root — Hermetica Encyclopedia
Root & Tuber · Root/Rhizome

Tiger's Claw Root

Moderate EvidenceCompound

Hermetica Superfood Encyclopedia

The Short Answer

Cat's claw root is a powerful Amazonian vine bark used to support immune function, reduce inflammation, and protect digestive health.

PubMed Studies
5
Validated Benefits
5
Synergy Pairings
At a Glance
CategoryRoot & Tuber
GroupRoot/Rhizome
Evidence LevelModerate
Synergy Pairings4

Health Benefits

Exhibits powerful anti-inflammatory effects by modulating inflammatory pathways through oxindole alkaloids and polyphenols.
Strengthens immune system function by enhancing white blood cell activity and overall immune resilience.
Delivers antioxidant protection by neutralizing free radicals, reducing oxidative stress, and supporting cellular longevity.
Promotes digestive health by soothing gastrointestinal inflammation, potentially alleviating ulcers, and improving gut resilience.
Demonstrates potential antiviral activity against certain viral infections through its immunomodulatory and protective compounds.

Origin & History

Tiger's Claw Root (Uncaria tomentosa), commonly known as Cat's Claw, is a woody vine native to the Amazon rainforest and tropical regions of Central and South America. It thrives in lush, humid jungle climates. This root is highly valued in traditional Amazonian medicine for its powerful anti-inflammatory, immune-modulating, and digestive-protective properties.

Tiger's Claw Root has been revered for centuries as a cornerstone of Amazonian healing traditions by Indigenous tribes. It was considered a sacred vine, traditionally used for warding off disease, restoring vitality, and nurturing the body’s natural defenses. Its enduring legacy now bridges ancient wisdom with modern botanical medicine, recognized for its profound health benefits.Traditional Medicine

Scientific Research

Scientific research, supported by overviews from NCCIH and Mount Sinai Health Library, validates Tiger's Claw Root's immune-boosting, anti-inflammatory, and antioxidant properties. Studies highlight its digestive-protective effects and potential in modulating inflammatory pathways. While promising, ongoing research continues to explore its full therapeutic spectrum.

Preparation & Dosage

Traditional Forms
Historically brewed by Indigenous Amazonian tribes into medicinal teas and decoctions for digestive disorders, infections, and inflammatory conditions.
Modern Forms
Available in capsules, tinctures, powders, and teas.
Applications
Incorporated into immune-supportive, anti-inflammatory, and digestive wellness protocols.
Recommended Dosage
250–1000mg daily; consultation with a healthcare provider is recommended for personalized dosage
Common ranges for standardized extract are .

Nutritional Profile

- Phytochemicals: Rich in oxindole alkaloids (pentacyclic and tetracyclic forms), which contribute to immune modulation. - Bioactives: Contains glycosides, tannins, flavonoids, and phytosterols, offering antioxidant, anti-inflammatory, and digestive benefits. - Sterols: Provides sterol fractions that support immune and cellular health.

Synergy Stack

Hermetica Formulation Heuristic
Foundational root base
Immune & Inflammation | Gut & Microbiome

Frequently Asked Questions

What is tiger's claw root (cat's claw)?
Tiger's claw root, more commonly known as cat's claw (Uncaria tomentosa), is a woody vine native to the Amazon rainforest. Its inner bark and root have been used for centuries by Indigenous Amazonian peoples to treat inflammation, infections, and digestive disorders. It contains oxindole alkaloids, flavonoids, and tannins with immune-modulating properties.
What is the recommended dosage and is cat's claw safe?
Standard dosages range from 250–1,000mg of standardized extract daily. It is generally well-tolerated but has significant drug interactions, particularly with immunosuppressants, blood thinners, and antihypertensives. It should be avoided during pregnancy, by organ transplant recipients, and by those with autoimmune conditions without medical supervision.
How does cat's claw compare to other immune-supporting herbs like echinacea?
Cat's claw works primarily through oxindole alkaloids that modulate immune cell activity, while echinacea stimulates innate immunity through alkylamides and polysaccharides. Cat's claw has stronger anti-inflammatory and antioxidant evidence, particularly for joint and digestive health. Echinacea has more clinical data for acute cold and flu prevention.

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.