
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Tejocote fruit contains high concentrations of flavonoids including epicatechin (4.32 mg/100mg dry weight) and catechin (9.17 mg/100mg), while the root contains digitalis-like compounds that inhibit sodium-potassium ATPase. The fruit provides antioxidant and cardiovascular benefits, but the root can cause dangerous cardiac toxicity mimicking digoxin poisoning.

Reported Benefits (Provisional)
Origin & History

Tejocote (*Crataegus mexicana*) is a fruit-bearing tree indigenous to Mexico and parts of Central America, particularly Guatemala. It thrives in temperate climates, favoring well-drained soils in mountainous regions between 3,000 and 8,000 feet elevation. This culturally significant fruit is valued in functional nutrition for its rich pectin, polyphenol, and vitamin C content.
Research Narrative (Provisional)
Studies validate Tejocote's significant antioxidant, anti-inflammatory, and cardioprotective properties, attributed to its rich polyphenol and pectin content. Research highlights its potential for cardiovascular, metabolic, and respiratory support. Ethnobotanical literature further confirms its widespread traditional use across Mexican highlands and deep cultural integration into traditional medicine.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Dietary fiber (high in pectin) - Vitamin C - Calcium - Iron - Magnesium - Potassium - Polyphenols - Flavonoids
Reported Mechanism (Provisional)
Tejocote fruit's flavonoids including epicatechin, catechin, and quercetin 3-D-galactoside provide antioxidant effects through free radical scavenging and enhance endothelial function via nitric oxide pathways. The root's digitalis-like compounds inhibit sodium-potassium ATPase at the same binding site as digoxin, increasing intracellular calcium and cardiac contractility. This mechanism also prolongs action potential duration and cardiac refractory period, producing antiarrhythmic effects.
Clinical Narrative (Provisional)
Clinical evidence is limited to case reports documenting cardiac toxicity rather than controlled efficacy trials. Two documented cases showed patients using tejocote root developed sinus bradycardia, Mobitz Type 1 heart block, and falsely elevated digoxin levels on immunoassays. Antioxidant activity is supported only by in vitro DPPH and FRAP assays showing seed extracts have the highest phenolic content and antioxidant capacity. No randomized controlled trials have validated the cardiovascular or weight loss benefits claimed in traditional use.
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