Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
The fruit of Sea Mango (Cerbera manghas) contains highly toxic cardiac glycosides, such as cerberin, which critically disrupt the Na+/K+-ATPase pump. Ingestion is lethal, causing severe cardiotoxicity and rendering it unsafe for any consumption.
Reported Benefits (Provisional)
Origin & History
Sea Mango (Cerbera manghas) is a tree native to coastal and mangrove regions of Southeast Asia, the Pacific Islands, and northern Australia. Thriving in tropical climates with saline-tolerant soils, its fruit is traditionally recognized for containing potent bioactive compounds. However, due to the presence of toxic alkaloids in its seeds and unripe fruit, it is primarily valued for its potential medicinal extracts rather than direct consumption.
Research Narrative (Provisional)
Preliminary research indicates Sea Mango contains bioactive compounds with antioxidant and anti-inflammatory properties. Further studies are needed to fully characterize its pharmacological potential and ensure safe applications, particularly given the plant's known toxicity.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Vitamins: C, A (as Beta-carotene) - Minerals: Potassium, Calcium - Dietary Fiber - Phytochemicals: Flavonoids, Polyphenols
Reported Mechanism (Provisional)
The primary toxic compounds, including cerberin, are cardiac glycosides that specifically inhibit the Na+/K+-ATPase pump located in cell membranes. This inhibition leads to an accumulation of intracellular sodium and subsequently calcium, disrupting normal electrochemical gradients. The resulting overload of calcium impairs cardiac muscle contraction and electrical conduction, culminating in severe cardiotoxicity.
Clinical Narrative (Provisional)
Due to its profound toxicity, no safe human clinical studies evaluating Sea Mango fruit for health benefits exist. Research is primarily focused on isolating and characterizing the potent cardiac glycosides responsible for its severe cardiotoxic effects, often conducted via in vitro or animal models to understand poisoning mechanisms. Any historical or traditional claims of medicinal properties are entirely overshadowed by its lethal potential, making the fruit unsuitable for therapeutic application.
Also Known As
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