Red Shiso — Hermetica Encyclopedia
Leaf & Herb · Leaf/Green

Red Shiso

Strong EvidenceCompound1 PubMed Study

Hermetica Superfood Encyclopedia

The Short Answer

A vibrant Japanese herb rich in antioxidants that may help ease seasonal allergies and support respiratory and immune health.

1
PubMed Studies
7
Validated Benefits
1
Synergy Pairings
At a Glance
CategoryLeaf & Herb
GroupLeaf/Green
Evidence LevelStrong
Synergy Pairings4

Health Benefits

Exhibits anti-allergic properties, alleviating seasonal allergies and soothing respiratory passages.
Enhances immune resilience through its potent antimicrobial, antiviral, and antioxidant actions.
Reduces oxidative stress and promotes cellular health via rosmarinic acid and anthocyanins.
Improves blood circulation and reduces arterial inflammation, supporting cardiovascular health.
Supports gut microbiome balance, alleviating bloating and enhancing overall digestion.
Promotes cognitive clarity and reduces inflammation through its omega-3 fatty acid content.
Enhances skin hydration and elasticity, contributing to overall skin health

Origin & History

Red Shiso (Perilla frutescens var. crispa) is an aromatic herb native to East Asia, particularly Japan, China, and Korea. Revered for its vibrant color and distinctive flavor, its leaves are also a powerhouse of bioactive compounds. It offers significant potential in functional nutrition, supporting respiratory health, immune function, and antioxidant defense.

Red Shiso has been deeply embedded in centuries of Japanese, Chinese, and Korean traditions, celebrated for its culinary excellence and medicinal properties. Historically, it was used for respiratory wellness, food preservation, and digestive support, symbolizing health and resilience. Its vibrant leaves continue to be revered, with modern science now validating its potent antioxidant, cardiovascular, immune, and anti-allergic benefits.Traditional Medicine

Scientific Research

Clinical research supports Red Shiso's potent anti-allergic, anti-inflammatory, and antioxidant properties, largely attributed to compounds like rosmarinic acid and anthocyanins. Studies indicate benefits for respiratory health, immune function, and cardiovascular support. Further research is exploring its potential in gut microbiome balance and skin health.

Preparation & Dosage

Common Forms
Fresh or dried leaves in cuisine and teas; standardized extracts and powders.
Traditional Culinary Use
Used in Japanese cuisine for pickling (umeboshi), salads, and rice dishes.
Tea Preparation
Brew dried leaves as herbal teas.
Dosage
500–1000 mg of standardized extract
Consume 1–3 grams of dried leaf daily or .

Nutritional Profile

- Vitamins: Vitamin A, Vitamin C - Minerals: Potassium, Calcium, Iron - Phytochemicals/Bioactives: Rosmarinic Acid, Anthocyanins, Alpha-Linolenic Acid (Omega-3), Flavonoids, Tannins, Perillaldehyde

Synergy Stack

Hermetica Formulation Heuristic
Polyphenol/antioxidant base
Immune & Inflammation | Gut & Microbiome

Frequently Asked Questions

What is Red Shiso?
Red Shiso (Perilla frutescens var. crispa) is an aromatic herb from the mint family, widely used in Japanese, Korean, and Chinese cuisine. Its deep purple-red leaves are rich in rosmarinic acid, anthocyanins, and omega-3 fatty acids, making it valued for both culinary and medicinal purposes.
How much Red Shiso should I take and is it safe?
Traditional use involves 1-3 grams of dried leaf daily as tea, or 500-1000 mg of standardized extract. Red Shiso is generally safe for most adults when consumed in food amounts. Those on blood-thinning medications should consult a healthcare provider, as it may have mild anticoagulant effects.
What are the main health benefits of Red Shiso?
Research highlights Red Shiso's anti-allergic properties, primarily attributed to rosmarinic acid, which inhibits inflammatory enzymes and histamine release. It also provides potent antioxidant protection from anthocyanins and supports cardiovascular health through its omega-3 content. Most human evidence is preliminary, with stronger data from in vitro and animal studies.

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.