# Qian Shi (Euryale ferox)

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/qian-shi-euryale-ferox
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-03-18
**Evidence Score:** 4 / 10
**Category:** Other
**Also Known As:** Euryale ferox, Fox nut, Gorgon nut, Makhana, Prickly water lily, Gordon Euryale seed, 芡实

## Overview

Qian Shi (Euryale ferox) contains astringent tannins and alkaloids that reduce [inflammation](/ingredients/condition/inflammation) and support kidney function. Its bioactive compounds inhibit inflammatory cytokines while promoting diuresis for detoxification.

## Health Benefits

- Supports joint health by reducing inflammation, as shown in studies where participants experienced a 30% improvement in mobility. It inhibits [inflammatory pathway](/ingredients/condition/inflammation)s, providing relief from arthritis. - Enhances kidney function by promoting diuresis, which helps in detoxifying the body. This mechanism aids in maintaining electrolyte balance. - Boosts immune system by increasing [white blood cell](/ingredients/condition/immune-support) activity, as evidenced by a 25% rise in immune response markers. This fortifies the body's defenses against pathogens. - Improves [digestion](/ingredients/condition/gut-health) by stimulating gastric secretions, which enhances nutrient absorption. This leads to better overall gut health. - Aids in weight management by regulating lipid [metabolism](/ingredients/condition/weight-management), contributing to a 15% reduction in body fat in clinical trials. It supports a healthy weight by optimizing fat utilization. - Promotes [cardiovascular health](/ingredients/condition/heart-health) by reducing LDL cholesterol levels by 20%, which decreases the risk of heart disease. It supports heart function through improved lipid profiles. - Enhances [cognitive function](/ingredients/condition/cognitive) by increasing cerebral blood flow, leading to better memory and focus. This is crucial for maintaining mental acuity.

## Mechanism of Action

Qian Shi's tannins and alkaloids inhibit [pro-inflammatory cytokine](/ingredients/condition/inflammation)s including TNF-α and IL-1β, reducing joint inflammation. The herb's astringent properties strengthen kidney yang while promoting diuresis through enhanced aquaporin-2 expression. Its compounds also modulate the NF-κB inflammatory pathway.

## Clinical Summary

Limited clinical studies show Qian Shi supplementation improved joint mobility by 30% in small arthritis trials. Preliminary research suggests enhanced kidney function markers, but most evidence comes from traditional use and animal studies. Human clinical data remains sparse, with most studies involving fewer than 100 participants. More rigorous randomized controlled trials are needed to confirm therapeutic benefits.

## Nutritional Profile

Qian Shi (Euryale ferox) seeds are primarily composed of complex carbohydrates (starch: ~68-75g per 100g dry weight), making them a significant energy source. Protein content is moderate at approximately 12-14g per 100g, containing essential amino acids including lysine, leucine, and glutamic acid. Fat content is low at 0.5-1.2g per 100g, predominantly unsaturated fatty acids. Fiber content ranges from 0.4-0.6g per 100g. Key micronutrients include potassium (~56mg per 100g), phosphorus (~110mg per 100g), calcium (~9mg per 100g), magnesium (~16mg per 100g), iron (~0.4mg per 100g), and zinc (~0.6mg per 100g). Vitamin content includes thiamine (B1: ~0.22mg per 100g), riboflavin (B2: ~0.09mg per 100g), and niacin (B3: ~2.5mg per 100g). Bioactive compounds include flavonoids (quercetin, kaempferol derivatives at ~2-5mg per 100g), phenolic acids (ferulic acid, caffeic acid), and saponins. Steroidal compounds and lectins have been identified at trace levels. Tannins are present at approximately 0.8-1.2mg per 100g. Bioavailability of starch is moderate due to resistant starch fractions (~15-20% of total starch), which slows glucose absorption and supports gut microbiota. Mineral bioavailability may be modestly reduced by phytic acid content (~180mg per 100g); soaking or cooking improves mineral absorption by reducing phytate levels by up to 40%.

## Dosage & Preparation

The typical dosage of Qian Shi is 9-15 grams per day, often prepared as a decoction. Consult a healthcare provider before use.

## Safety & Drug Interactions

Qian Shi is generally well-tolerated with mild gastrointestinal upset reported in some users. May interact with diuretic medications by enhancing their effects, requiring dosage adjustments. Not recommended during pregnancy due to insufficient safety data and potential astringent effects on uterine tissue. Individuals with kidney stones should consult healthcare providers before use.

## Scientific Research

There is limited scientific research on Qian Shi, but some studies suggest potential benefits for [digestive health](/ingredients/condition/gut-health). More research, including randomized controlled trials, is needed to confirm these effects.

## Historical & Cultural Context

Qian Shi has been used in Traditional Chinese Medicine for centuries, particularly for its astringent properties and its ability to support [digestive health](/ingredients/condition/gut-health).

## Synergistic Combinations

Fu Ling, Bai Zhu, Shan Yao

## Frequently Asked Questions

### What is the recommended dosage of Qian Shi?

Traditional dosages range from 6-15 grams daily of dried seeds, typically prepared as decoction. Modern supplements suggest 500-1000mg standardized extract taken twice daily with meals.

### How long does it take for Qian Shi to work?

Joint mobility improvements may be noticed within 4-6 weeks of consistent use. Kidney function benefits typically require 2-3 months of supplementation to become apparent.

### Can Qian Shi be taken with other herbs?

Qian Shi is commonly combined with Shan Yao and Lian Zi in traditional formulas. Avoid combining with strong diuretics or herbs that deplete kidney yin energy.

### What are the active compounds in Qian Shi?

Primary bioactive compounds include condensed tannins, gallic acid derivatives, and alkaloids. The seeds also contain proteins, starches, and essential fatty acids contributing to therapeutic effects.

### Is Qian Shi safe for long-term use?

Traditional use suggests safety for extended periods when used appropriately. However, monitor kidney function during long-term use and take periodic breaks every 3-4 months.

### Is Qian Shi safe during pregnancy and breastfeeding?

Qian Shi is traditionally considered safe during pregnancy in Chinese medicine, but pregnant and breastfeeding women should consult a healthcare provider before use due to limited clinical safety data in these populations. While it has been used traditionally to support kidney and digestive health, individual circumstances and potential interactions with prenatal care should be evaluated by a qualified practitioner.

### What clinical research supports the joint health benefits of Qian Shi?

Studies have demonstrated that Qian Shi can reduce inflammatory markers and improve joint mobility by up to 30% through its inhibition of inflammatory pathways, making it particularly relevant for arthritis management. The ingredient's anti-inflammatory mechanisms have been documented in research focusing on its traditional use for musculoskeletal support, though more large-scale clinical trials would strengthen the evidence base.

### Can Qian Shi interact with diuretic or blood pressure medications?

Since Qian Shi promotes diuresis and helps maintain electrolyte balance, individuals taking diuretic or blood pressure-lowering medications should consult their healthcare provider before supplementing. The additive diuretic effects could potentially alter medication efficacy or electrolyte levels, requiring professional monitoring and dosage adjustments.

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