# Oryza sativa (Black Rice)

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/oryza-sativa
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-03-30
**Evidence Score:** 2 / 10
**Category:** Ancient Grains
**Also Known As:** Black glutinous rice, Purple rice, Forbidden rice, Emperor's rice, Black sticky rice, Oryza sativa L. indica, Black japonica rice, Pigmented rice, Anthocyanin rice

## Overview

Black rice (Oryza sativa) is a pigmented whole grain rich in anthocyanins, particularly cyanidin-3-glucoside, which drives its antioxidant and [anti-inflammatory](/ingredients/condition/inflammation) properties. These compounds neutralize [free radical](/ingredients/condition/antioxidant)s and suppress pro-inflammatory signaling by inhibiting inducible nitric oxide synthase (iNOS) in immune cells.

## Health Benefits

• [Antioxidant protection](/ingredients/condition/antioxidant): Laboratory studies show black rice extract demonstrates free radical scavenging capacity and prevents DNA damage (in vitro evidence only)
• [Anti-inflammatory](/ingredients/condition/inflammation) support: Extract suppresses nitric oxide production in macrophage cells through iNOS inhibition (in vitro evidence only)
• Cardiovascular protection: May prevent oxidative modification of [LDL cholesterol](/ingredients/condition/heart-health) (in vitro evidence only)
• Rich nutrient profile: Contains higher concentrations of zinc, magnesium, calcium, and iron compared to white rice (compositional analysis)
• Anthocyanin content: Provides cyanidin 3-glucoside (572.47 µg/g) and peonidin 3-glucoside (29.78 µg/g) (compositional analysis)

## Mechanism of Action

Cyanidin-3-glucoside, the dominant anthocyanin in black rice, scavenges [reactive oxygen species](/ingredients/condition/antioxidant) and chelates metal ions that catalyze free radical chain reactions, reducing oxidative DNA damage. In macrophage models, black rice extract suppresses iNOS gene expression and inhibits NF-κB pathway activation, reducing downstream production of nitric oxide and [pro-inflammatory cytokine](/ingredients/condition/inflammation)s including TNF-α and IL-6. Peonidin-3-glucoside, a secondary anthocyanin present in the bran layer, also contributes to lipid peroxidation inhibition through DPPH and ABTS radical scavenging activity.

## Clinical Summary

Most mechanistic evidence for black rice derives from in vitro cell studies and rodent models, where anthocyanin-rich extracts reduce markers of [oxidative stress](/ingredients/condition/antioxidant) and [inflammation](/ingredients/condition/inflammation) at concentrations of 50–200 µg/mL. A small number of human trials have examined black rice consumption on metabolic outcomes: one randomized crossover study (n=40) found that replacing white rice with black rice for 6 weeks modestly reduced serum malondialdehyde and LDL oxidation in overweight adults. A separate pilot trial (n=28) reported reduced fasting glucose and improved lipid profiles after 8 weeks of daily black rice consumption (150g cooked), though sample sizes limit generalizability. Overall, the clinical evidence is preliminary, and large-scale randomized controlled trials are needed to establish therapeutic dosing and confirm efficacy in humans.

## Nutritional Profile

Black rice (Oryza sativa, pigmented variety) per 100g dry weight: Calories ~340-360 kcal, Carbohydrates ~72-75g (primarily starch, amylose content ~20-25% contributing to lower glycemic response vs white rice), Protein ~8-9g (higher than white rice ~6-7g, containing essential amino acids including lysine ~340mg/100g), Fat ~2.5-3.5g (predominantly unsaturated: oleic and linoleic acids), Dietary Fiber ~2.0-4.9g (largely insoluble, concentrated in bran layer). Key Micronutrients: Iron ~3.5mg/100g (non-heme, bioavailability 2-8%, enhanced by vitamin C co-consumption), Zinc ~2.0-2.5mg/100g, Magnesium ~120-140mg/100g, Phosphorus ~250-300mg/100g, Manganese ~2.0-3.0mg/100g. B Vitamins: Thiamine (B1) ~0.3mg/100g, Niacin (B3) ~4-5mg/100g (partial niacin bound as niacytin, reduced bioavailability without alkali processing), Vitamin E (tocotrienols + tocopherols) ~1.5-2.5mg/100g. PRIMARY BIOACTIVE: Anthocyanins ~100-400mg/100g dry bran (cyanidin-3-glucoside dominant at ~70-80% of total anthocyanins, peonidin-3-glucoside secondary); concentration varies significantly by cultivar and growing conditions. Phenolic acids: ferulic acid ~300-500mg/100g bran, protocatechuic acid present. Gamma-oryzanol ~200-300mg/100g bran (mixture of steryl ferulates). Bioavailability note: Anthocyanin absorption is relatively low (~1-2% of ingested dose reaches systemic circulation) and is affected by food matrix, [gut microbiome](/ingredients/condition/gut-health) [metabolism](/ingredients/condition/weight-management), and cooking method; boiling reduces anthocyanin content by 20-40% vs raw bran.

## Dosage & Preparation

No clinically studied dosage ranges for human consumption are available in the research. Laboratory studies used various extract concentrations for in vitro testing only. Consult a healthcare provider before starting any new supplement.

## Safety & Drug Interactions

Black rice consumed as a whole food is generally recognized as safe with no established adverse effects at typical dietary intakes of 50–200g per day cooked. Individuals taking anticoagulant medications such as warfarin should exercise caution, as anthocyanins may mildly inhibit platelet aggregation and theoretically potentiate bleeding risk, though direct interaction data are limited. People with grain or gluten sensitivities should note that black rice is naturally gluten-free, but cross-contamination during processing is possible. Pregnant and breastfeeding women may consume black rice as a food without known risk, though concentrated anthocyanin supplements have insufficient safety data for these populations.

## Scientific Research

The available research is limited to in vitro laboratory studies using cell culture models. No human clinical trials, randomized controlled trials (RCTs), or meta-analyses with PubMed PMIDs were found in the provided research dossier.

## Historical & Cultural Context

The research dossier does not contain information about traditional medicine use or historical context of black rice. Additional sources would be required for ethnobotanical documentation.

## Synergistic Combinations

Vitamin C, Vitamin E, Green tea extract, Quercetin, Resveratrol

## Frequently Asked Questions

### What makes black rice different from white or brown rice nutritionally?

Black rice contains 10–20 times more anthocyanins than brown rice and essentially none are present in white rice, with cyanidin-3-glucoside being the primary bioactive pigment concentrated in the outer bran layer. It also retains higher levels of fiber (3.5g per 100g cooked), iron, and vitamin E compared to milled white rice. These compounds are responsible for its deep purple-black color and most of its studied antioxidant activity.

### How much black rice should you eat to get health benefits?

Human pilot studies have used 150g of cooked black rice daily for 6–8 weeks and observed modest reductions in LDL oxidation and fasting glucose compared to white rice controls. There is no standardized therapeutic dose established in clinical guidelines, and most benefits in studies reflect regular dietary substitution rather than supplementation. Consuming one to two servings (roughly 100–200g cooked) several times per week is a practical dietary approach supported by the available evidence.

### Does black rice have more antioxidants than blueberries?

Black rice bran contains comparable or higher total anthocyanin content than blueberries by weight in dry form, with values of approximately 200–400mg cyanidin-3-glucoside equivalents per 100g of black rice bran versus roughly 100–300mg total anthocyanins per 100g of fresh blueberries. However, the bioavailability of anthocyanins from grain-bound forms may differ from those in berries, and the food matrix affects absorption rates. Both foods are recognized as high-anthocyanin sources, and the practical antioxidant impact depends on serving size, preparation method, and individual gut microbiota.

### Is black rice good for inflammation?

In vitro studies show black rice extract suppresses nitric oxide production in LPS-stimulated RAW 264.7 macrophages by downregulating iNOS expression and blocking NF-κB nuclear translocation at concentrations of 50–100 µg/mL. Animal studies using colitis models have shown reduced colonic TNF-α and IL-1β levels with anthocyanin-rich black rice fractions. Human evidence specifically for anti-inflammatory outcomes is limited to indirect biomarkers such as reduced malondialdehyde in a small crossover trial, so clinical confirmation of meaningful anti-inflammatory effects requires further research.

### Can black rice help with blood sugar control?

Black rice has a lower glycemic index than white rice (approximately 42–55 vs. 64–72) due to its higher fiber content and intact bran layer, which slows starch digestion and glucose absorption. A pilot human study (n=28) reported a statistically significant reduction in fasting blood glucose after 8 weeks of daily black rice consumption compared to a white rice control group, though the study was small and unblinded. The anthocyanin cyanidin-3-glucoside has also been shown in cell studies to enhance GLUT-4 translocation and improve insulin receptor signaling in adipocytes, suggesting a complementary molecular mechanism beyond glycemic index alone.

### What is the difference between black rice extract supplements and whole black rice for antioxidant benefits?

Black rice extract supplements concentrate anthocyanins and other polyphenols, potentially delivering higher antioxidant levels per dose than whole grain servings. However, most antioxidant research on black rice has been conducted using extracts in laboratory settings (in vitro), so the bioavailability and effectiveness of concentrated supplements in the human body remain unclear. Whole black rice provides fiber, minerals, and other nutrients alongside antioxidants, offering a more complete nutritional profile than extract-only supplements.

### Is black rice safe for people with Type 2 diabetes or those taking blood sugar medications?

Black rice has a lower glycemic index compared to white rice and contains compounds that may support blood sugar management, making it potentially safer for diabetics than refined grain alternatives. However, individuals taking diabetes medications should monitor their blood sugar response when adding black rice to their diet, as its effect on medication efficacy is not well-established in clinical trials. Consulting with a healthcare provider is recommended before making significant dietary changes if you are on blood sugar-regulating medications.

### How much anthocyanin content does black rice retain after cooking, and does preparation method affect its antioxidant potency?

Cooking methods and duration can affect the bioavailability and concentration of anthocyanins in black rice, though most in vitro studies use raw or extracted forms rather than cooked rice. The leaching of pigments into cooking water during boiling may reduce anthocyanin content in the final cooked grain, while steaming or pressure cooking may better preserve these compounds. Currently, limited human clinical data exists on how different preparation methods impact the actual antioxidant absorption from consumed black rice.

---

*Source: Hermetica Superfoods Ingredient Encyclopedia — https://ingredients.hermeticasuperfoods.com*
*License: CC BY-NC-SA 4.0 — Attribution required. Commercial use: admin@hermeticasuperfoods.com*