Neem Leaves (Azadirachta indica) — Hermetica Encyclopedia
USDA Nutrient-Dense Foods · Traditional Medicinal Herbs

Neem Leaves (Azadirachta indica) (Azadirachta indica)

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The Short Answer

Neem leaves are a traditional Ayurvedic herb rich in antioxidants and nutrients, primarily studied in laboratory settings for potential health benefits.

PubMed Studies
0
Validated Benefits
Synergy Pairings
At a Glance
CategoryUSDA Nutrient-Dense Foods
GroupTraditional Medicinal Herbs
Evidence LevelPreliminary

Health Benefits

Origin & History

Neem leaves come from the neem tree (Azadirachta indica), a fast-growing evergreen native to the Indian subcontinent and cultivated in tropical and semitropical regions. The leaves are harvested fresh or dried and contain limonoids (tetranortriterpenoids), proteins (7.1%), carbohydrates (22.9%), and various amino acids and minerals.

Neem has been used for centuries in Ayurvedic medicine and South Asian traditional systems as a household remedy for skin diseases, inflammation, and infections. Historical use spans millennia, with documentation in ancient texts noting its bitter principles for various ailments.Traditional Medicine

Scientific Research

The research dossier reveals a critical gap: no human clinical trials, RCTs, or meta-analyses were found for neem leaves. Available evidence is limited to preclinical antioxidant studies showing methanolic extract IC50 values of 6.65 mg/ml for DPPH radical scavenging, with no PubMed PMIDs provided for human studies.

Preparation & Dosage

No clinically studied dosage ranges for neem leaves in humans are available. Preclinical studies use methanolic or ethanolic extracts without specified standardization or doses. Consult a healthcare provider before starting any new supplement.

Nutritional Profile

Synergy Stack

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Frequently Asked Questions

What is neem leaves?
Neem leaves come from the Azadirachta indica tree native to India, containing limonoids, proteins (7.1%), carbohydrates (22.9%), and various bioactive compounds traditionally used in Ayurvedic medicine.
What are the benefits of neem leaves?
Based on preclinical research, neem leaves show antioxidant activity through free radical scavenging and may support cellular protection. Traditional uses include skin health and general wellness, though human clinical trials are lacking.
What is the recommended dosage?
No clinically studied human dosages are available. Traditional preparations use various forms including aqueous, ethanolic, or methanolic extracts. Always consult a healthcare provider before use.
Are there any side effects?
The research provides no specific safety data, contraindications, or drug interactions for neem leaves. While azadirachtin is reported as non-toxic in pesticide contexts, comprehensive human safety profiles are unavailable.
Can I take neem leaves with other supplements?
No drug interaction data is available from clinical studies. Given the lack of human safety trials, consult your healthcare provider before combining neem with other supplements or medications.

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