# Metabolaid (Hibiscus sabdariffa and Lippia citriodora)

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/metabolaid
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-03-29
**Evidence Score:** 2 / 10
**Category:** Other
**Also Known As:** Hibiscus sabdariffa and Lippia citriodora extract, Hibiscus-Lemon Verbena complex, Roselle and Lemon Verbena extract, Red sorrel and Lippia citriodora blend, Hibiscus-Lippia polyphenolic extract, Karkade and Lemon Verbena combination, Jamaica and Verveine extract

## Overview

Metabolaid is a patented blend of Hibiscus sabdariffa and Lippia citriodora extracts. It supports weight management by significantly increasing satiety hormones and suppressing appetite, leading to reductions in body weight and fat.

## Health Benefits

• Weight loss of 2-4 kg over 8-12 weeks demonstrated in multiple RCTs (n=184+ participants)
• Body fat reduction of 7% and belly fat decrease of 7.5% shown in 84-person placebo-controlled trial
• Appetite suppression through 13-55% increase in GLP-1 and ghrelin suppression for 4 hours (clinical evidence)
• Waist circumference reduction of 6 cm demonstrated in combined trials (n=100)
• Improved metabolic markers including [blood pressure](/ingredients/condition/heart-health), cholesterol, and blood sugar (multiple trials)

## Mechanism of Action

Metabolaid primarily modulates appetite and [metabolism](/ingredients/condition/weight-management). It increases Glucagon-Like Peptide-1 (GLP-1) levels by 13-55%, promoting satiety, while simultaneously suppressing ghrelin, the hunger hormone, for up to four hours. These actions lead to reduced caloric intake and contribute to overall fat reduction.

## Clinical Summary

Multiple randomized controlled trials (RCTs) involving over 184 participants demonstrated Metabolaid's efficacy, showing a consistent weight loss of 2-4 kg over 8-12 weeks. An 84-person placebo-controlled trial further revealed a significant 7% reduction in total body fat and a 7.5% decrease in belly fat. Clinical evidence also confirms appetite suppression, linked to a 13-55% increase in GLP-1 and ghrelin suppression for four hours.

## Nutritional Profile

Metabolaid is a patented combination extract standardized from two botanical sources: Hibiscus sabdariffa (calyx/flower extract) and Lippia citriodora (lemon verbena leaf extract), typically dosed at 500mg total per serving in clinical trials. Bioactive compounds in Hibiscus sabdariffa component include anthocyanins (primarily delphinidin-3-sambubioside and cyanidin-3-sambubioside, approximately 10-15% of hibiscus extract), hydroxycitric acid derivatives, hibiscus acid, polyphenols including chlorogenic acids, and flavonoids such as quercetin and kaempferol glycosides. Lippia citriodora component is standardized for polyphenols primarily verbascoside (acteoside, approximately 15-25% of lemon verbena extract), luteolin glycosides (luteolin-7-diglucuronide and luteolin-7-glucuronide), and rosmarinic acid. The combined formulation provides an estimated 80-100mg total polyphenols per 500mg dose. Fiber content is minimal as it is a concentrated extract. Protein and fat content are negligible (<1%). Micronutrients present in trace amounts include vitamin C (from hibiscus source), iron, and calcium, though at sub-therapeutic concentrations. Bioavailability is enhanced by the synergistic polyphenol matrix; verbascoside from Lippia citriodora shows moderate gut absorption with colonic microbial [metabolism](/ingredients/condition/weight-management) producing active metabolites; anthocyanins from hibiscus demonstrate low-to-moderate bioavailability (approximately 1-5% absorption) but exert significant gut-level activity influencing incretin hormones (GLP-1 pathway). The combination is theorized to act synergistically on appetite-regulating hormones rather than through direct nutrient provision.

## Dosage & Preparation

Clinical studies consistently used 500 mg/day of Metabolaid extract in capsule form, taken as a single daily dose for 8-12 weeks. No data available for powder forms or alternative dosages. Consult a healthcare provider before starting any new supplement.

## Safety & Drug Interactions

Metabolaid is generally well-tolerated in clinical studies, with no serious adverse effects reported. However, individuals who are pregnant, nursing, or have pre-existing medical conditions should consult a healthcare professional before use. Due to its metabolic effects, caution is advised for those taking medications that impact blood sugar or appetite. Comprehensive long-term safety data and potential drug interactions require further research.

## Scientific Research

Eight clinical trials with over 450 participants have evaluated Metabolaid, including a key 12-week RCT (n=84) showing 2 kg weight loss without diet changes. Additional published RCTs include PMC7022485 examining obesity treatment and PMC8854308 demonstrating appetite reduction, with an ongoing trial (NCT03568877) investigating AMPK activation.

## Historical & Cultural Context

No traditional use data was found for the Hibiscus-Lippia combination specifically, as Metabolaid is a modern branded formula. While hibiscus has individual folk uses in African and Asian systems for hypertension and [digestion](/ingredients/condition/gut-health), the combined extract lacks documented traditional context.

## Synergistic Combinations

Green tea extract, chromium picolinate, garcinia cambogia, conjugated linoleic acid, fiber supplements

## Frequently Asked Questions

### What is Metabolaid primarily used for?

Metabolaid is primarily used for weight management, offering significant reductions in body weight, total body fat, and belly fat. It achieves these effects by supporting appetite control and modulating metabolic processes.

### How much weight can one expect to lose with Metabolaid?

Clinical trials indicate that users can expect a weight loss of 2-4 kg over an 8-12 week period. This consistent reduction is supported by multiple randomized controlled trials involving over 184 participants.

### How does Metabolaid reduce body fat?

Metabolaid contributes to body fat reduction by influencing metabolic pathways and reducing caloric intake. An 84-person placebo-controlled trial demonstrated a 7% reduction in total body fat and a 7.5% decrease in belly fat, including visceral fat.

### Does Metabolaid help with appetite control?

Yes, Metabolaid effectively helps with appetite control. It achieves this by increasing GLP-1 levels by 13-55%, a hormone that promotes satiety, and by suppressing ghrelin, the hunger hormone, for up to four hours after consumption.

### What are the main components of Metabolaid?

Metabolaid is a proprietary blend of two specific plant extracts: Hibiscus sabdariffa and Lippia citriodora. These two botanical ingredients work synergistically to provide its clinically studied weight management and metabolic benefits.

### Is Metabolaid safe to take with blood pressure or diabetes medications?

Metabolaid contains hibiscus sabdariffa, which has mild blood pressure-lowering properties and may potentiate antihypertensive or glucose-regulating medications. Individuals taking medications for blood pressure or diabetes should consult their healthcare provider before supplementing with Metabolaid to avoid additive effects. Clinical trials have not extensively evaluated drug interactions, so professional medical guidance is recommended.

### What is the recommended dosage of Metabolaid for weight loss results?

Clinical trials demonstrating 2-4 kg weight loss over 8-12 weeks typically used standardized extract doses, though specific dosing protocols vary by formulation. The optimal daily dose should align with the product's label instructions and the studied extract concentration of hibiscus and lemon verbena. Consistency over 8+ weeks appears necessary to observe meaningful body composition changes based on available research.

### Who is the ideal candidate for Metabolaid supplementation?

Metabolaid is most beneficial for adults with overweight or obesity seeking appetite control and gradual fat loss, particularly those with elevated belly fat or metabolic concerns. The ingredient is not recommended for pregnant or nursing women, children, or individuals with uncontrolled blood pressure or diabetes without medical supervision. Those already taking weight-loss medications or with caffeine sensitivity should evaluate compatibility with their existing regimen.

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*Source: Hermetica Superfoods Ingredient Encyclopedia — https://ingredients.hermeticasuperfoods.com*
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