Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Irvingia gabonensis, commonly known as African mango, contains seed extracts rich in fiber and bioactive compounds that inhibit adipogenesis and enhance lipolysis. The extract works by suppressing leptin resistance and inhibiting the transcription factor PPAR-gamma, leading to reduced fat cell formation and increased fat burning.
Reported Benefits (Provisional)
Origin & History
Irvingia gabonensis, or African Mango, is a fruit-bearing tree native to West Africa. The seeds are particularly valued for their potential health benefits and are often used in supplements.
Research Narrative (Provisional)
Some clinical trials suggest African Mango may aid in weight loss and improve cholesterol levels, but more research is needed to confirm these findings.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
{"macronutrients": {"carbohydrates": "15-20 g per 100 g", "protein": "7-8 g per 100 g", "fats": "15-18 g per 100 g"}, "micronutrients": {"vitamins": {"Vitamin C": "11 mg per 100 g", "Vitamin A": "0.5 mg per 100 g"}, "minerals": {"Calcium": "120 mg per 100 g", "Iron": "2.5 mg per 100 g", "Magnesium": "120 mg per 100 g", "Potassium": "300 mg per 100 g"}}, "bioactive_compounds": {"fiber": "8-10 g per 100 g", "polyphenols": "0.5-1 g per 100 g", "flavonoids": "0.2-0.5 g per 100 g"}, "bioavailability_notes": "The bioavailability of nutrients like calcium and iron may be affected by the presence of fiber and phytates. Vitamin C can enhance iron absorption, while the fat content aids in the absorption of fat-soluble vitamins."}
Reported Mechanism (Provisional)
African mango seed extract inhibits the transcription factor PPAR-gamma (peroxisome proliferator-activated receptor gamma), which reduces adipocyte differentiation and fat storage. The extract's high fiber content binds bile acids, forcing the liver to convert cholesterol into new bile acids and lowering serum cholesterol levels. Additionally, it enhances insulin sensitivity by modulating adiponectin levels and reducing inflammatory cytokines like TNF-alpha.
Clinical Narrative (Provisional)
Multiple randomized controlled trials involving 200-300 participants have demonstrated African mango's efficacy for weight management. A 10-week study showed participants lost an average of 28 pounds compared to 1 pound in placebo groups, with 150mg twice daily dosing. Clinical trials also report 26% reductions in total cholesterol and 27% decreases in LDL cholesterol levels. However, most studies are relatively short-term (8-12 weeks) and larger, longer-duration trials are needed to confirm long-term safety and efficacy.
Also Known As
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