
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
African mango (Irvingia gabonensis) contains IGOB131, a standardized seed extract that influences leptin sensitivity and fat metabolism. The extract works by inhibiting C-reactive protein production and enhancing adiponectin secretion to support weight management.

Reported Benefits (Provisional)
Origin & History

African Mango, also known as Irvingia gabonensis, is native to the tropical rainforests of West Africa. The fruit and its seeds have been used for centuries in traditional African medicine.
Research Narrative (Provisional)
Studies suggest that African mango may aid in weight management and improve metabolic parameters. However, more research is needed to confirm these effects.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Rich in fiber and healthy fats. - Contains essential vitamins and minerals. - Provides antioxidants. - Low in sugar compared to other fruits.
Reported Mechanism (Provisional)
IGOB131 in African mango inhibits glycerol-3-phosphate dehydrogenase, reducing fat cell formation and triglyceride storage. The extract enhances leptin receptor sensitivity in the hypothalamus while increasing adiponectin levels, which improves insulin sensitivity. Additionally, it reduces C-reactive protein production, decreasing systemic inflammation that interferes with metabolism.
Clinical Narrative (Provisional)
A 10-week randomized controlled trial with 102 participants showed 6% body fat reduction and 22% blood glucose decrease using 150mg IGOB131 twice daily. A separate 8-week study demonstrated 28-pound average weight loss and 26% total cholesterol reduction. Most studies use standardized IGOB131 extract rather than whole fruit, with sample sizes ranging from 40-102 participants. Evidence is promising but limited to short-term studies from a small number of research groups.
Also Known As
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