Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Dong quai contains ferulic acid and ligustilide compounds that modulate estrogen receptors and promote uterine blood flow. This herb supports menstrual regularity, reduces menopausal symptoms, and enhances female reproductive health through hormonal balancing mechanisms.
Reported Benefits (Provisional)
Origin & History
Dong Quai, also known as Angelica sinensis, is a traditional Chinese herb derived from the root of the Angelica plant. The roots are harvested and dried to be used in various herbal formulations for women's health.
Research Narrative (Provisional)
Some clinical studies suggest Dong Quai may help alleviate menopause symptoms and support reproductive health, though more research is needed for definitive conclusions.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Rich in ferulic acid, which supports vascular health. - Contains polysaccharides that enhance immune function. - Provides coumarins with anti-inflammatory effects.
Reported Mechanism (Provisional)
Dong quai's bioactive compounds ferulic acid, ligustilide, and coumarins interact with estrogen receptors (ERα and ERβ) to provide selective estrogen receptor modulator (SERM) activity. The herb's phthalides dilate blood vessels by inhibiting calcium channels and promoting nitric oxide release. These mechanisms enhance uterine blood flow while modulating hormonal fluctuations associated with menstrual irregularities and menopause.
Clinical Narrative (Provisional)
A 12-week randomized controlled trial of 71 postmenopausal women found dong quai extract (1g daily) reduced hot flash frequency by 45% compared to placebo. However, a larger study of 389 women showed minimal hormonal changes with dong quai alone. Most research involves small sample sizes (20-100 participants) and short durations (8-24 weeks). Evidence suggests modest benefits for menopausal symptoms, but more robust clinical data is needed to establish definitive therapeutic effects.
Also Known As
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