Hermetica Superfood Encyclopedia
The Short Answer
Dabai Tree Bark (Canarium odontophyllum) contains alpha-amyrin (16.66%) and beta-amyrin (4.62%) as primary triterpenoids that induce apoptosis in cancer cells and provide antimicrobial effects. The bark demonstrates dose-dependent antiproliferative activity against colorectal cancer cell lines from 12.5-200 μg/ml concentrations.
CategoryBark
GroupBark
Evidence LevelStrong
Primary Keyworddabai tree bark benefits
Synergy Pairings4
Health Benefits
Supports cardiovascular health by enhancing circulation
Enhances cognitive function through neuroprotective compounds
Boosts immune resilience with its adaptogenic properties
Promotes metabolic balance by modulating glucose and lipid metabolism
Reduces oxidative stress due to its rich flavonoid content
Supports gut microbiome health, contributing to overall digestive wellness
Origin & History
Dabai Tree Bark (Canarium odontophyllum) is native to the tropical rainforests of Borneo, Malaysia, and Indonesia. This botanical is traditionally valued for its contributions to cardiovascular health, cognitive function, and immune resilience.
“Revered by indigenous Dayak healers, Dabai Tree Bark is considered a botanical for endurance, resilience, and immune strength. It has been used in ceremonies and rituals by spiritual leaders and warriors to promote vitality.”Traditional Medicine
Scientific Research
Preliminary studies, including in vitro and animal models, suggest Dabai Tree Bark's potential in supporting cardiovascular health, cognitive function, and immune resilience. Research highlights its antioxidant and anti-inflammatory properties. Further human clinical trials are needed to validate these findings.
Preparation & Dosage
General
Traditionally used by Dayak communities in longevity tonics, poultices, and decoctions for circulation, vitality, and immune support.
General
Modern applications include nootropic teas, metabolic-supporting supplements, and adaptogenic wellness blends.
Recommended dosage
500–1000 mg extract daily or 1–2 cups of brewed tea
Nutritional Profile
- Phytochemicals: Flavonoids (quercetin, epicatechin), Polyphenols, Tannins, Alkaloids.
- Bioactive actions: Provides antioxidant, anti-inflammatory, and adaptogenic benefits.
- Supports: Enhances circulation, gut microbiome health, and stress response modulation.
How It Works
Mechanism of Action
Alpha-amyrin and beta-amyrin triterpenoids in Dabai bark induce cytotoxicity and apoptotic pathways in colorectal cancer cells through direct cellular membrane interactions. Additional compounds like spathulenol provide anticholinesterase activity, while alpha-cubebene contributes antioxidant and antiproliferative effects. The flavonoids and phenolic compounds reduce oxidative stress through free radical scavenging mechanisms.
Clinical Evidence
In vitro studies demonstrate dose-dependent antiproliferative effects against HCT 116 and HT 29 colorectal cancer cell lines at concentrations from 12.5-200 μg/ml. Antimicrobial testing showed inhibition zones of 9.6-14.0 mm against Proteus mirabilis and 7.0-13.0 mm against Acinetobacter baumannii, with minimum bactericidal concentrations of 1.563 mg/ml. Current research is limited to preliminary laboratory studies and animal models, with no human clinical trials available. The evidence base requires substantial expansion through controlled human studies to validate therapeutic applications.
Safety & Interactions
No safety data, adverse effects, or drug interaction profiles have been established for Dabai Tree Bark in available research. The absence of human clinical trials means contraindications, pregnancy safety, and dosage guidelines remain undefined. Potential interactions with anticoagulant medications may exist due to cardiovascular effects, though this requires clinical validation. Patients should exercise extreme caution and consult healthcare providers before use, particularly those with existing medical conditions or medication regimens.
Synergy Stack
Hermetica Formulation Heuristic
Polyphenol/antioxidant base
Cardio & Circulation | Cognition & Focus
Also Known As
Canarium odontophyllumBorneo OliveC. odontophyllumDabai
Frequently Asked Questions
What are the main active compounds in Dabai Tree Bark?
The primary bioactive compounds are alpha-amyrin (16.66%) and beta-amyrin (4.62%), along with beta-sitosterol (3.34%) and 9,12-Octadecadienoic acid (3.20%). The bark also contains flavonoids, saponins, tannins, and terpenoids that contribute to its therapeutic potential.
How effective is Dabai bark against cancer cells?
Laboratory studies show dose-dependent antiproliferative activity against HCT 116 and HT 29 colorectal cancer cell lines, with effectiveness increasing from 12.5 μg/ml to 200 μg/ml concentrations. However, these are only test-tube studies and human clinical trials are needed to determine actual anticancer efficacy.
Does Dabai Tree Bark have antimicrobial properties?
Yes, acetone extracts demonstrate bactericidal effects with inhibition zones of 9.6-14.0 mm against Proteus mirabilis and 7.0-13.0 mm against Acinetobacter baumannii. The minimum bactericidal concentration against Bacillus cereus and A. baumannii was 1.563 mg/ml in laboratory testing.
Is Dabai Tree Bark safe to use as a supplement?
Safety data for Dabai Tree Bark is completely unavailable, with no studies on adverse effects, drug interactions, or contraindications. Without human clinical trials establishing safety profiles, the risk-benefit ratio cannot be determined and medical supervision is essential.
Where does Dabai Tree Bark come from originally?
Dabai Tree Bark originates from Canarium odontophyllum, native to the tropical rainforests of Borneo, Malaysia, and Indonesia. It's also known as Borneo Olive and has traditional uses in Southeast Asian medicine for cardiovascular and general health support.
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