Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Cranberry 30% proanthocyanidins is a concentrated fruit extract standardized to contain 30% proanthocyanidins, particularly A-type proanthocyanidins. These compounds prevent bacterial adhesion to urinary tract walls and provide potent antioxidant activity through free radical scavenging.
Reported Benefits (Provisional)
Origin & History
Cranberries are native to North America and have been used for centuries in traditional medicine. The extract standardized to 30% proanthocyanidins is derived from the fruit.
Research Narrative (Provisional)
Research supports the use of cranberry extract for urinary tract health, primarily through preventing bacterial adhesion. Further studies are needed to explore additional health benefits.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- High in proanthocyanidins, a type of antioxidant. - Contains vitamin C and dietary fiber. - Low in calories and free from fat.
Reported Mechanism (Provisional)
A-type proanthocyanidins in cranberry prevent bacterial adhesion by binding to P-fimbriae on E. coli bacteria, blocking their attachment to uroepithelial cells in the urinary tract. These compounds also scavenge reactive oxygen species through their polyphenolic structure, donating hydrogen atoms to neutralize free radicals and reduce oxidative damage at the cellular level.
Clinical Narrative (Provisional)
Multiple randomized controlled trials involving over 3,000 participants demonstrate cranberry proanthocyanidins reduce UTI recurrence by 35-50% in women with recurrent infections. A 2017 Cochrane review of 50 studies found moderate evidence for UTI prevention, with optimal doses requiring 36mg proanthocyanidins daily. Most studies used standardized extracts for 6-12 months, showing consistent but modest protective effects. Evidence is strongest for prevention rather than treatment of active infections.
Also Known As
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