Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Coriander seed (Coriandrum sativum) contains up to 73.5% linalool in its essential oils, along with phenolic compounds that provide antioxidant, antimicrobial, and metabolic benefits. The bioactive compounds work through DPPH radical scavenging, Nrf2 pathway activation, and cholesterol displacement by phytosterols like β-sitosterol.
Reported Benefits (Provisional)
Origin & History
Coriander Seed (Coriandrum sativum) is native to the Mediterranean, Middle Eastern, and Southern European regions, and is now cultivated globally in temperate climates. This aromatic seed is a versatile botanical, highly valued for its digestive, metabolic, and cognitive benefits.
Research Narrative (Provisional)
Numerous scientific studies, including in vitro, animal, and some human trials, support Coriander Seed's efficacy in promoting digestive health, regulating blood sugar, and exhibiting anti-inflammatory and antimicrobial properties. Research highlights the role of its essential oils and phenolic compounds in these benefits.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Macronutrients: Dietary Fiber - Vitamins: B-vitamins - Minerals: Iron, Magnesium, Potassium, Calcium - Phytochemicals/Bioactives: Essential oils (Linalool, α-Pinene, γ-Terpinene), Flavonoids, Phenolic compounds, Polyphenols
Reported Mechanism (Provisional)
Coriander seed's primary bioactive linalool (up to 73.5%) and phenolic compounds (15.55-64.99 mg GAE/g extract) scavenge DPPH radicals with IC50 values of 756.43 μg/mL while activating the Nrf2 antioxidant pathway through Keap1 modification. Phytosterols including stigmasterol and β-sitosterol displace cholesterol in intestinal micelles and modulate HMG-CoA reductase activity. Essential oil components like α-pinene (5.3-6.37%) and camphor (8.34-44.99%) disrupt bacterial cell growth, showing antimicrobial zones of 14.3mm against S. aureus.
Clinical Narrative (Provisional)
Current evidence for coriander seed is primarily based on in vitro studies and animal models rather than human clinical trials. Laboratory studies demonstrate antioxidant activity with DPPH scavenging rates of 1.053-2.221 mg/mL and antimicrobial effects against common pathogens. Animal studies show blood glucose reduction and increased insulin levels in diabetic rat models, but specific quantified outcomes from human trials are not available. The evidence strength is limited by the lack of randomized controlled trials in human populations.
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