# Chitrak (Plumbago zeylanica)

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/chitrak-plumbago-zeylanica
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-03-18
**Evidence Score:** 4 / 10
**Category:** Other
**Also Known As:** Plumbago zeylanica, Ceylon Leadwort, White Leadwort, Doctorbush, Wild Leadwort, 火炭母草, Agni, Vahni

## Overview

Chitrak (Plumbago zeylanica) contains plumbagin, a naphthoquinone compound that stimulates [digestive enzyme](/ingredients/condition/gut-health)s and enhances gastric acid secretion. This Ayurvedic herb works by activating digestive fire (agni) and inhibiting [pro-inflammatory cytokine](/ingredients/condition/inflammation)s through NF-κB pathway modulation.

## Health Benefits

- Chitrak enhances digestion by stimulating [digestive enzyme](/ingredients/condition/gut-health)s, reducing bloating and indigestion. - It has anti-inflammatory properties that alleviate joint pain by inhibiting [inflammatory pathway](/ingredients/condition/inflammation)s. - Chitrak supports weight management by boosting [metabolism](/ingredients/condition/weight-management) and promoting fat breakdown. - It exhibits [antimicrobial](/ingredients/condition/immune-support) activity, protecting against infections by inhibiting bacterial growth. - Chitrak enhances [liver function](/ingredients/condition/detox) by promoting detoxification, as evidenced by improved liver enzyme profiles. - It may improve respiratory health by reducing mucus and easing symptoms of asthma. - Chitrak supports [skin health](/ingredients/condition/skin-health) by reducing acne and promoting a clear complexion through its antibacterial effects.

## Mechanism of Action

Plumbagin, the primary bioactive compound in chitrak, stimulates pancreatic lipase and amylase enzymes to enhance [digestion](/ingredients/condition/gut-health). It inhibits cyclooxygenase (COX-2) and lipoxygenase pathways, reducing [inflammatory](/ingredients/condition/inflammation) mediators like TNF-α and IL-6. The compound also activates [thermogenesis](/ingredients/condition/weight-management) by increasing AMP-activated protein kinase (AMPK) activity, promoting fat oxidation.

## Clinical Summary

Limited clinical research exists on chitrak, with most evidence from animal studies and traditional use. A small pilot study (n=30) showed 15% improvement in digestive symptoms after 4 weeks of chitrak supplementation. Animal studies demonstrate significant [anti-inflammatory](/ingredients/condition/inflammation) effects with 50-100mg/kg plumbagin doses. More rigorous human trials are needed to establish therapeutic efficacy and optimal dosing protocols.

## Nutritional Profile

Chitrak (Plumbago zeylanica) is not consumed as a food source for macronutrient value; it is primarily a medicinal herb valued for its bioactive phytochemical profile. Key bioactive compound: Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), the principal active constituent found predominantly in the root bark at concentrations of approximately 0.5–1.5% dry weight (some reports up to 2.5% depending on geographical origin and harvest conditions). Other notable compounds include: 3,3'-biplumbagin (~0.01–0.05%), chitranone (a binaphthoquinone), zeylanone, isozeylanone, elliptinone, and droserone. Phenolic acids and flavonoids are present in minor quantities, contributing to overall [antioxidant](/ingredients/condition/antioxidant) capacity. Terpenoids and sterols including beta-sitosterol (~0.1–0.3%) and stigmasterol have been identified in root and aerial parts. Tannins are present at approximately 2–5% in root extracts. Minerals detected in root tissue include calcium (~1.2–2.0 mg/g), iron (~0.3–0.8 mg/g), zinc (~0.02–0.06 mg/g), magnesium (~0.8–1.5 mg/g), and potassium (~1.0–2.5 mg/g), though these are not significant dietary sources given the small medicinal doses used. Crude fiber content in dried root material is approximately 10–15%, crude protein approximately 5–8%, and total ash content approximately 4–7%. The herb contains trace amounts of vitamins but is not a meaningful source. Plumbagin exhibits moderate oral bioavailability (estimated ~30–40% in preclinical models) with rapid absorption but also rapid hepatic [metabolism](/ingredients/condition/weight-management); co-administration with lipid-based carriers or piperine may enhance bioavailability. Plumbagin is lipophilic (LogP ~1.97), facilitating membrane permeability but also contributing to dose-dependent toxicity at higher concentrations. Typical Ayurvedic therapeutic dosage of root powder is 250–500 mg/day, meaning actual plumbagin intake is approximately 1.25–7.5 mg per dose. Caution: plumbagin is cytotoxic at elevated doses and the herb is classified as a potent (tikshna) drug in Ayurveda, not suitable for unsupervised or prolonged use.

## Dosage & Preparation

Chitrak is usually taken as a root powder or decoction, with a dosage of 250-500 mg per day. Consult a healthcare provider before use.

## Safety & Drug Interactions

Chitrak can cause gastric irritation, nausea, and skin sensitivity in some individuals due to its heating properties. It may interact with anticoagulant medications by enhancing their effects through plumbagin's blood-thinning properties. Pregnant and breastfeeding women should avoid chitrak as it may stimulate uterine contractions. Individuals with gastric ulcers or hyperacidity should use caution due to its gastric acid-stimulating effects.

## Scientific Research

Research on Chitrak is limited, but some studies suggest it may have [anti-inflammatory](/ingredients/condition/inflammation) and digestive-stimulating properties. More clinical research is needed.

## Historical & Cultural Context

Chitrak has been valued in Ayurvedic medicine for its ability to enhance [digestion](/ingredients/condition/gut-health) and [metabolism](/ingredients/condition/weight-management), often used in formulations for weight management.

## Synergistic Combinations

Ginger, Black Pepper, Long Pepper

## Frequently Asked Questions

### What is the recommended dosage of chitrak powder?

Traditional Ayurvedic texts recommend 1-3 grams of chitrak root powder daily, typically divided into two doses. Start with 500mg twice daily with meals to assess tolerance, as higher doses may cause gastric irritation.

### How long does chitrak take to improve digestion?

Most users report improved digestive symptoms within 2-4 weeks of consistent chitrak use. The herb's enzyme-stimulating effects may be noticed within days, but sustained benefits for chronic digestive issues typically require 4-6 weeks.

### Can chitrak help with weight loss?

Chitrak may support weight management by increasing metabolic rate and enhancing fat breakdown through AMPK activation. However, it works best as part of a comprehensive approach including proper diet and exercise rather than as a standalone weight loss solution.

### Is chitrak safe for people with diabetes?

Chitrak may help regulate blood sugar levels, but diabetics should consult healthcare providers before use. The herb can potentially enhance the effects of diabetes medications, requiring blood glucose monitoring and possible dosage adjustments.

### What are the side effects of taking too much chitrak?

Excessive chitrak consumption can cause severe gastric irritation, burning sensation, nausea, and skin rashes. Overdose symptoms include excessive sweating, increased heart rate, and digestive upset due to its intensely heating nature in Ayurvedic terms.

### Does chitrak interact with common medications like blood thinners or antihistamines?

Chitrak may have mild anticoagulant properties and could potentially interact with blood-thinning medications like warfarin or aspirin, requiring medical supervision. Additionally, as chitrak stimulates digestive enzymes and has antimicrobial activity, it may affect the absorption or efficacy of certain oral medications, antihistamines, and antacids. Always consult with a healthcare provider or Ayurvedic practitioner before combining chitrak with prescription medications to avoid adverse interactions.

### Is chitrak safe to take during pregnancy and breastfeeding?

Chitrak is traditionally contraindicated during pregnancy due to its potent digestive stimulant and thermogenic (heat-generating) properties, which may stimulate uterine contractions or cause excessive metabolic heat. Safety during breastfeeding is also not well-established in clinical research, so nursing mothers should avoid supplementation unless explicitly recommended by their Ayurvedic practitioner. Pregnant and lactating women should consult their healthcare provider before using any chitrak products.

### What is the difference between chitrak powder, chitrak oil, and chitrak extracts in terms of effectiveness?

Chitrak powder is the most traditionally used form in Ayurvedic medicine and provides a broad spectrum of the plant's active compounds, while chitrak oil (infused in carrier oils) is better absorbed through topical application for joint pain and inflammation. Standardized chitrak extracts concentrate specific bioactive alkaloids and may offer faster results for digestive support, but powders are generally considered more balanced for long-term use. The most effective form depends on your specific health goal—powder for digestion, oil for localized inflammation, and extracts for targeted metabolic support.

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*Source: Hermetica Superfoods Ingredient Encyclopedia — https://ingredients.hermeticasuperfoods.com*
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