Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Bhumyamalaki (Phyllanthus niruri) contains phyllanthin and hypophyllanthin, lignans that protect liver cells from oxidative damage and support hepatic detoxification pathways. The herb demonstrates significant hepatoprotective effects by inhibiting lipid peroxidation and reducing elevated liver enzymes.
Reported Benefits (Provisional)
Origin & History
Bhumyamalaki, also known as Phyllanthus niruri, is a small herb found in tropical regions. It is commonly used in traditional medicine for its hepatoprotective properties.
Research Narrative (Provisional)
Studies on Bhumyamalaki suggest its efficacy in supporting liver health and treating viral infections. Some research includes animal studies and preliminary human trials.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
Bhumyamalaki (Phyllanthus niruri) is a medicinal herb with a complex phytochemical profile rather than a conventional macronutrient-rich food source. Macronutrient composition per 100g dried herb: crude protein approximately 10-14g, crude fiber 15-20g, carbohydrates approximately 40-50g, crude fat 2-4g, moisture content 8-12%. Key bioactive lignans include phyllanthin (0.5-1.2% dry weight) and hypophyllanthin (0.3-0.8% dry weight), which are primary hepatoprotective agents. Flavonoids present include quercetin, rutin, and astragalin at concentrations of 0.8-2.5% total flavonoid content. Tannins, particularly geraniin and corilagin (ellagitannins), are found at 4-8% dry weight and contribute to antiviral and antioxidant activity. Alkaloids including phyllantidine and phyllantine are present at trace levels (0.01-0.05%). Triterpenoids such as phyllantol and cymene occur at approximately 0.1-0.5%. Mineral content includes potassium (800-1200mg/100g), calcium (200-400mg/100g), magnesium (150-250mg/100g), iron (15-25mg/100g), and zinc (3-6mg/100g). Vitamin C is present at approximately 25-60mg/100g in fresh plant material, significantly reduced upon drying. Gallic acid and ellagic acid are present at 1-3% dry weight. Phenolic acids including caffeic and ferulic acid contribute to total polyphenol content of 8-15% dry weight. Bioavailability note: lignans and ellagitannins show moderate oral bioavailability; absorption of phyllanthin is enhanced with lipid co-administration due to its lipophilic nature; standardized extracts typically normalized to 0.5-1% phyllanthin content for therapeutic consistency.
Reported Mechanism (Provisional)
Bhumyamalaki's primary bioactive compounds phyllanthin and hypophyllanthin inhibit hepatic cytochrome P450 enzymes while enhancing glutathione S-transferase activity, promoting Phase II detoxification. The herb's geraniin and corilagin tannins exhibit antioxidant properties by scavenging free radicals and reducing lipid peroxidation in liver tissue. Additionally, the plant's alkaloids modulate immune function by activating macrophage phagocytic activity and stimulating cytokine production.
Clinical Narrative (Provisional)
Human trials involving 120-180 participants with hepatitis B showed Bhumyamalaki reduced ALT and AST liver enzymes by 35-40% over 30 days compared to placebo. Smaller studies (n=40-60) demonstrated significant reduction in kidney stone recurrence rates and improved urinary citrate levels. However, most clinical evidence comes from short-term studies with limited sample sizes, requiring larger long-term trials to confirm sustained benefits. The hepatoprotective effects appear most pronounced in acute liver stress rather than chronic conditions.
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