Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
AstraGin is a patented combination of Astragalus membranaceus and Panax notoginseng standardized for astragalosides and ginsenosides. It enhances nutrient absorption by upregulating intestinal transporters including SGLT1, CAT1, and GLUT4, increasing bioavailability of amino acids, vitamins, and other nutrients by up to 50%.
Reported Benefits (Provisional)
Origin & History
Patented blend of Astragalus membranaceus and Panax notoginseng root extracts, developed by NuLiv Science in the United States. Standardized for astragalosides and ginsenosides to enhance nutrient absorption across the intestinal wall.
Research Narrative (Provisional)
Clinical studies demonstrate AstraGin increases amino acid absorption by up to 62%, glucose absorption by 55%, and vitamin absorption by 50%. Research published in the Journal of Agricultural and Food Chemistry shows enhanced intestinal transporter expression via AMPK pathway activation.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
AstraGin is a patented combination extract consisting of Astragalus membranaceus and Panax notoginseng, standardized to contain astragalosides (including Astragaloside IV) from Astragalus and notoginsenosides (primarily Rb1, Rg1) from Panax notoginseng. Typical supplemental doses range from 25–50mg per serving. It is not a significant source of macronutrients, vitamins, or minerals in supplemental form. The primary bioactive compounds are saponins and polysaccharides that upregulate intestinal transport proteins — specifically SGLT-1 (sodium-glucose transporter), CAT-1 (cationic amino acid transporter), and GLUT2 — increasing mRNA expression of these transporters by 40–60% in intestinal epithelial cells. Astragaloside IV contributes adaptogenic and immunomodulatory activity via polysaccharide fractions, while notoginsenosides contribute anti-inflammatory and circulatory support. Bioavailability of AstraGin itself is modest due to its large molecular weight saponins, but its mechanism is local gut-level transporter upregulation rather than systemic absorption.
Reported Mechanism (Provisional)
AstraGin's astragalosides and ginsenosides activate the mTOR pathway and upregulate intestinal nutrient transporters including SGLT1 for glucose, CAT1 for amino acids, and GLUT4 for enhanced cellular uptake. The compound increases ATP production in enterocytes, providing energy for active transport processes. Additionally, AstraGin modulates tight junction proteins to optimize intestinal permeability for nutrient absorption.
Clinical Narrative (Provisional)
Human studies demonstrate AstraGin increases absorption of amino acids by 41.5%, citrulline by 45%, and various vitamins by 25-50% compared to placebo groups. A 28-day randomized controlled trial with 32 participants showed significant increases in plasma amino acid levels when combined with protein supplementation. Animal studies consistently show enhanced bioavailability across multiple nutrient classes, though more large-scale human trials are needed to establish optimal dosing protocols.
Also Known As
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