# Amur Maple Seeds (Acer ginnala)

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/amur-maple-seeds-acer-ginnala
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-04-05
**Evidence Score:** 2 / 10
**Category:** Seed
**Also Known As:** Acer ginnala seeds, Amur maple samaras, Ginnala maple seeds, Siberian maple seeds, River maple seeds, Flame maple seeds, Tatarian maple seeds, Chinese maple seeds

## Overview

Amur Maple Seeds (Acer ginnala) contain bioactive polyphenols, including gallic acid and ellagic acid, which drive their antioxidant activity by scavenging [reactive oxygen species](/ingredients/condition/antioxidant) and inhibiting lipid peroxidation. These compounds also modulate NF-κB inflammatory signaling, positioning the seeds as a candidate for oxidative stress and [inflammation](/ingredients/condition/inflammation)-related applications.

## Health Benefits

The Amur Maple is a small, deciduous tree that produces winged seeds, commonly known as samaras. These seeds have been utilized in traditional medicine for their potential health benefits, including [antioxidant](/ingredients/condition/antioxidant) and [anti-inflammatory](/ingredients/condition/inflammation) properties. Although not as commonly consumed as other seeds, Amur Maple seeds are studied for their potential applications in natural remedies, particularly in strengthening the [immune system](/ingredients/condition/immune-support) and supporting vascular health.

## Mechanism of Action

The primary bioactives in Amur Maple Seeds, gallic acid and ellagic acid, inhibit NF-κB pathway activation, thereby reducing downstream [pro-inflammatory cytokine](/ingredients/condition/inflammation) production including TNF-α and IL-6. Gallic acid also directly scavenges superoxide anion and hydroxyl radicals, while ellagic acid inhibits cyclooxygenase (COX) enzymes, dampening the arachidonic acid cascade. Additionally, tannin-class compounds present in the seeds chelate transition metal ions, further limiting Fenton reaction-driven oxidative damage.

## Clinical Summary

Research on Amur Maple Seeds remains largely at the in vitro and animal model stage, with no large-scale randomized controlled trials in humans published to date. Rodent studies have demonstrated measurable reductions in malondialdehyde (a [lipid peroxidation](/ingredients/condition/antioxidant) marker) and elevated superoxide dismutase activity following seed extract administration. Phytochemical analyses consistently confirm high polyphenol content, but translational evidence establishing effective human dosages, bioavailability, and clinical endpoints is absent. The overall evidence base is preliminary, and conclusions about therapeutic efficacy in humans should be drawn cautiously.

## Nutritional Profile

- Antioxidant: Contains compounds that help combat [oxidative stress](/ingredients/condition/antioxidant) and reduce cellular damage.
- [Anti-inflammatory](/ingredients/condition/inflammation): May reduce inflammation in the body, helping conditions like arthritis.
- Vascular Health: Traditionally used for improving blood circulation and strengthening blood vessels. Detailed compositional analysis of Amur Maple Seeds (Acer ginnala) shows the presence of essential micronutrients including B-vitamins (thiamin, riboflavin, niacin), fat-soluble vitamins, and a mineral profile including potassium, phosphorus, and trace elements. The total dietary fiber fraction includes both soluble and insoluble components contributing to satiety and gut health.

## Dosage & Preparation

Recommended Dosage: Whole: 1-2 tablespoons (10-20g) daily, soaked or sprinkled on meals. Ground: 1-2 tablespoons (10-20g) mixed into smoothies, oatmeal, or baking. Oil: 1-2 tablespoons (15ml) drizzled on food.

Traditional Use & Preparation: - Harvest when samaras are mature and brown.
- Remove the winged outer covering to access the seeds.
- Seeds can be consumed raw, roasted, or added to recipes like salads, trail mixes, and granola.
- Roasting enhances flavor, and care should be taken to avoid contamination from pesticides or pollutants.
- Foraging should be conducted responsibly, especially as the tree is invasive in certain areas.

General Guidance: Start with a lower dose and increase gradually. Consult a healthcare provider before starting any new supplement, especially if pregnant, nursing, or taking medications.

## Safety & Drug Interactions

Amur Maple Seeds have no established human safety profile from controlled clinical trials, making definitive contraindication lists difficult to compile. Given their tannin content, high doses may inhibit iron and zinc absorption, posing a risk for individuals with mineral deficiencies or those on iron supplementation therapy. Gallic acid constituents may theoretically potentiate anticoagulant medications such as warfarin by inhibiting platelet aggregation, warranting caution in patients on blood thinners. Pregnant and breastfeeding women should avoid supplementation due to a complete absence of reproductive safety data.

## Scientific Research

Amur Maple seeds have been part of traditional herbal medicine, particularly in Eastern Asia. Their [antioxidant](/ingredients/condition/antioxidant) and [anti-inflammatory](/ingredients/condition/inflammation) effects are significant, with research suggesting potential vascular health benefits. While not widely used in mainstream diets, their health-promoting properties are gaining attention.

## Historical & Cultural Context

While not commonly consumed in modern diets, Amur maple seeds have been used in traditional Chinese medicine as part of broader herbal practices. The tree itself is valued for its ornamental beauty and its adaptability to a variety of climates. The seeds are not widely cultivated for food, but they are an interesting wild edible for those who forage.

## Synergistic Combinations

Hermetica Synergy Stack (Formulation Heuristic)
Role: Fat + fiber base (metabolic stability)
Intention: Immune & [Inflammation](/ingredients/condition/inflammation) | Cardio & Circulation
Primary Pairings: Sunflower Seeds (Helianthus annuus); Pumpkin Seeds (Cucurbita pepo); Chia Seeds
Evidence: see study_urls / reference_urls

## Frequently Asked Questions

### What are the main active compounds in Amur Maple Seeds?

Amur Maple Seeds are characterized by significant concentrations of gallic acid, ellagic acid, and hydrolyzable tannins such as gallotannins. These polyphenolic compounds are responsible for the seeds' documented antioxidant capacity in laboratory settings, with gallic acid in particular showing potent free radical scavenging activity against DPPH and ABTS radicals in in vitro assays.

### Are Amur Maple Seeds safe to eat or supplement with?

There is currently no established safe dosage or formal safety assessment for Amur Maple Seed supplementation in humans. The seeds' tannin content can inhibit digestive enzyme activity and reduce absorption of dietary minerals like iron and zinc at higher intake levels. Until human clinical data are available, supplementation should only be considered under the guidance of a qualified healthcare provider.

### Do Amur Maple Seeds have anti-inflammatory properties?

Yes, in vitro and animal studies suggest that seed extracts from Acer ginnala suppress inflammation by inhibiting NF-κB transcription factor activation and reducing production of cytokines such as TNF-α and IL-1β. Ellagic acid within the seeds also inhibits COX-1 and COX-2 enzymes, enzymes central to prostaglandin synthesis and the inflammatory response. However, these effects have not been confirmed in human clinical trials.

### How do Amur Maple Seeds compare to other antioxidant seeds like grape seeds?

Grape seed extract is far more extensively researched, with proanthocyanidins as its primary bioactives and multiple human trials documenting cardiovascular and antioxidant benefits at doses of 100–300 mg/day. Amur Maple Seeds share overlapping polyphenol classes like gallic acid but lack the standardized extracts and clinical validation that grape seed products possess. Until comparative bioavailability and efficacy studies are conducted, Amur Maple Seeds cannot be positioned as equivalent or superior to grape seed extract.

### Can Amur Maple Seeds interact with blood thinning medications?

There is a theoretical risk of interaction between Amur Maple Seed polyphenols, particularly gallic acid, and anticoagulant or antiplatelet drugs such as warfarin, aspirin, or clopidogrel, because gallic acid has demonstrated platelet aggregation inhibition in laboratory models. This additive effect could potentially increase bleeding risk, though no human pharmacokinetic interaction studies have confirmed this. Patients taking blood thinners should consult their physician before using any Acer ginnala-derived supplement.

### What is the most bioavailable form of Amur Maple Seeds for supplementation?

Amur Maple seeds are typically available as standardized extracts, powders, or whole seed preparations, with standardized extracts offering potentially higher bioavailability of active compounds like polyphenols and flavonoids. The extraction process can concentrate the seed's antioxidant constituents, making them more readily absorbed compared to whole seeds. However, clinical evidence directly comparing bioavailability between forms is limited, so consult with a practitioner to determine the most suitable form for your needs.

### Who benefits most from Amur Maple Seed supplementation?

Individuals seeking natural antioxidant support, particularly those interested in traditional Asian medicine approaches, may benefit from Amur Maple seeds, though evidence is strongest for their general antioxidant potential rather than for specific conditions. People looking to diversify their polyphenol intake beyond common sources like grape seed or green tea may also find value in this less-common seed. Those with specific health concerns should consult a healthcare provider before adding Amur Maple seeds to their regimen.

### What does current clinical research show about the effectiveness of Amur Maple Seeds?

Research on Amur Maple seeds remains limited compared to more widely studied seeds, with most evidence emerging from laboratory and traditional medicine contexts rather than large-scale human trials. Available studies suggest potential antioxidant and anti-inflammatory activity, but robust clinical evidence supporting specific health claims in humans is still developing. More rigorous clinical research is needed to establish reliable dosing recommendations and confirm health benefits in human populations.

## References

Foraging guides; Wild edible resources; Traditional herbal medicine texts; | Sources: https://www.researchgate.net/publication/332356171_The_antioxidant_activity_of_Acer_ginnala_samara_extract; https://www.sciencedirect.com/science/article/abs/pii/S0378874119303281

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